Our Work on Opioid Addiction

Nicotine Remains a Tremendous Market Opportunity

… And Is Costing Healthcare Billions

Addiction Creates a Socioeconomic Disadvantage 88.7% of Black Americans diagnosed with substance use disorder did not seek treatment Lower socioeconomic status have higher harm despite same or lower consumption at rate of 2-5X

PTSD: A Large Market Starving for Pharmacotherapies

Current PTSD Treatments are Lacking Medications only help minimize frequency & severity of PTSD symptoms (antidepressants sertraline and paroxetine) 20-40% of patients do not respond

Standard of Care: Psychotherapy treatments – inadequate Patients often do not complete therapy Up to 50% do not respond

VA PTSD Psychopharmacology Working Group “Urgent need to find effective pharmacologic treatments for PTSD should be considered a national mental health priority”

Neuroepigenetic Platform for Addiction